Electroceuticals

Electroceutical Science and Medicine

Our work in electroceutical science and medicine, funded by Clayton Foundation for Medical Research, studies energy-efficient and selective stimulation of neurons and neural circuits. We are working on creating a science and technology platform that will catalyze the development of a new class of medical devices for optimizing neural stimuli. We hypothesize that non-traditional, customized waveforms can produce more energetically-efficient and selective stimulation. We are developing novel algorithms to find efficient waveform, as well as discovering the mechanisms underlying how these non-traditional waveforms are unlocking different access mechanisms for selective stimulation.

Ongoing Projects:

Developing Algorithms that can Optimize Stimulus Waveforms for Electroceutical Devices

Promoting Fairness in Machine Learning Predictions with Medical Data

Key Publications:

Chang J, Paydarfar D. Falling off a limit cycle using phase-agnostic stimuli: Applications to clinical oscillopathies. Chaos. 2021 Feb;31(2):023134. doi: 10.1063/5.0032974. PMID: 33653068.

Chang J, Paydarfar D. Optimizing stimulus waveforms for electroceuticals. Biol Cybern. 2019 Apr;113(1-2):191-199. doi: 10.1007/s00422-018-0774-x. Epub 2018 Aug 11. PMID: 30099589.

Chang J, Paydarfar D. Optimizing stimulus waveforms for suppressing epileptic activity reveals a counterbalancing mechanism. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:2226-2229. doi: 10.1109/EMBC.2018.8512762. PMID: 30440848.